LOS GAMETOS DE ERIZO DE MAR COMO MODELO DE ESTUDIO DE LA FECUNDACIÓN
Resumen
RESUMEN
Los gametos de erizo de mar son excelentes modelos para estudiar las bases moleculares de la fecundación y del desarrollo embrionario. Estudios realizados por varios grupos de investigación así como el nuestro han permitido entender algunos de los mecanismos moleculares que regulan tanto la fisiología del espermatozoide y del óvulo como el desarrollo temprano del erizo de mar. PALABRAS CLAVE: Espermatozoide, óvulo, fecundación
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REFERENCIAS
Alves, A.P., Mulloy, B., Diniz J.A. and Mourao, P.A. (1997). Sulfated polysaccharides from the egg jelly layer are species-specific inducers of acrosomal reaction in sperms of sea urchins. J. Biol. Chem. 272: 6965-6971.
Beltrán, C., Galindo, B.E., Rodríguez-Miranda, E. and Sánchez, D. (2007a). Signal transduction mechanisms regulating ion fluxes in the sea urchin sperm. Signal Transduction. 7: 103-117.
Beltrán, C., Vacquier, V.D., Moy, G., Chen, Y., Buck, J., Levin, L.R. and Darszon, A. (2007b). Particulate and soluble adenylyl cyclases participate in the sperm acrosome reaction. Biochem Biophys Res Commun. 13;358(4):1128-35.
Carrol, E.J. (1976). Cortical granule proteases from sea urchin eggs. Methods Enzymol. 54:343-353.
Christen, R., Schackmann, R.W. and Shapiro, B.M. (1982). Elevation of the intracellular pH activates respiration and motility of sperm of the sea urchin, Strongylocentrotus purpuratus. J. Biol. Chem. 257:14881-14890.
Covian-Nares, F., Martínez-Cadena, G., Lopez-Godínez, J., Voronina, E., Wessel, G.M. and Garcia-Soto, J. (2004). A Rho-signaling pathway mediates cortical granule translocation in the sea urchin oocyte. Mech. Dev. 121(3): 225-35.
Cuéllar-Mata, P., Martínez-Cadena, G., López-Godínez, J., Obregón, A. and García-Soto, J. (2000). The GTP-binding protein RhoA localizes to the cortical granules of Strongylocentrotus purpuratus sea urchin egg and is secreted during fertilization. Eur. J. Cell Biol. 79:81-91.
De la Sancha, C.U., Martínez-Cadena, G., López-Godínez, J., Castellano, L.E., Nishigaki, T., Darszon, A. and García-Soto, J. (2007). Rho-kinase (ROCK) in sea urchin sperm: its role in regulating the intracellular pH during the acrosome reaction. Biochem. Biophys. Res. Commun. 364(3): 470-5.
Darszon, A., Nishigaki, T., Wood, C., Trevino, C.L., Felix, R. and Beltran, C. (2005). Calcium channels and Ca2+ fluctuations in sperm physiology. Int. Rev. Cytol. 243:79-172.
Darszon, A., Guerrero, A., Galindo, B.E., Nishigaki, T., and Wood, C.D. (2008). Sperm-activating peptides in the regulation of ion fluxes, signal transduction and motility. Nt. J. Dev. Biol. 52: 595 – 606.
Darszon, A., Acevedo, J.J., Galindo, B.E., Hernández-González, E.O., Nishigaki, T., Treviño, C.L., Wood, C. and Beltrán, C. (2006). Sperm channel diversity and functional multiplicity. Reproduction. 131(6):977-88.
Hirohashi, N., and Vacquier, V.D. (2002). Egg fucose sulfate polymer, sialoglycan and speract all trigger the sea urchin sperm acrosome reaction. Biochem. Biophys. Res. Commun.. 296: 833-839.
Inaba, K. (2003). Molecular architecture of the sperm flagella: molecules for motility and signaling. Zoolog. Sci. 20:1043-56.
Iftinca, M., Hamid, J., Chen, L., Varela, D., Tadayonnejad, R., Altier, C., Turner, R.W. and Zamponi, G.W. (2007). Regulation of T-type calcium channels by Rho-associated kinase. Nat. Neurosci. 10(7): 854-60.
Kiela, P.R., Xu, H. and Ghishan, F.K. (2006). Apical NA+/H+ exchangers in the mammalian gastrointestinal tract. J. Physiol. Pharmacol. 57(7): 51-79.
Kuo, R.C., Baxter, G.T., Thompson, S.H., Stricker, S.A., Patton, C., Bonaventura, J. and Eppel, D. (2000). NO is necessary and sufficient for egg activation and fertilization. Nature 406:633-636.
Lee, H.C. (1984). Sodium and proton transport in flagella isolated from sea urchin spermatozoa. J. Biol. Chem. 259:4957-63.
Leguia, M. and Wessel, G. (2007). The many faces of egg activation at fertilization. Signal Transduction 7: 118-141.
López-Godínez, J., Garambullo, T.I., Martínez-Cadena, G. and García-Soto, J. (2003). Mastoparan induces Ca2+-independent cortical granule exocytosis in sea urchin eggs. Biochem. Biophys. Res. Commun. 301(1): 13-6.
Manzo, S., Martínez-Cadena, G., López-Godínez, J., Pedraza-Reyes, M. and García-Soto, J. (2003). A Rho GTPase controls the rate of protein synthesis in the sea urchin egg. Biochem. Biophys. Res. Commun. 310(3): 685-90.
Mourao, P.A. (2007). A carbohydrate-based mechanism of species recognition in sea urchin fertilization. Brazilian J. Med. Biol. Res. 40:5-17.
Molich, A. and Heisler, N. (2005). Determination of pH by microfluorometry: intracellular and interstitial pH regulation in developing early-stage fish embryos (Danio rerio). J. Exp. Biol. 208(21): 4137-49.
Rangel-Mata, F., Méndez-Márquez, R., Martínez-Cadena, G., López-Godínez, J., Nishigaki, T., Darszon, A. and García-Soto, J. (2007). Rho, Rho-kinase, and the actin cytoskeleton regulate the Na+ -H+ exchanger in sea urchin eggs. Biochem. Biophys. Res. Commun. 352(1): 264-9.
Riento, K. and Ridley, A.J. (2003). Rocks: multifunctional kinases in cell behaviour. Nat. Rev. Mol. Cell Biol. 4(6): 446-56.
Roux, M.M., Radeke, M.J., Goel, M., Mushegian, A. and Foltz, K.R. (2008). 2DE identification of proteins exhibiting turnover and phosphorylation dynamics during sea urchin egg activation. Dev. Biol. 313(2): 630-47.
Sardet, D. and Tilney, L. (1970). Origin of acrosomal precess is actin complexed with membrane precursos? Cell Biol. Rep. 1:193-200.
SeGall, G.K. and Lennarz, W.J. (1981). Jelly coat and induction of the acrosome reaction in echinoid sperm. Dev. Biol. 86(1): 87-93.
Schmandke, A. and Strittmatter, S.M. (2007). ROCK and Rho: biochemistry and neuronal functions of Rho-associated protein kinases. Neuroscientist. 13(5): 454-69.
Shum, W.W., Le, G.Y., Jones, R.L., Gurney, A.M. and Sasaki ,Y. (2003). Involvement of Rho-kinase in contraction of guinea-pig aorta induced by prostanoid EP3 receptor agonists. Br. J. Pharmacol. 139(8): 1449-61.
Sodergren, E., G. M. Weinstock, et al. (2006). The genome of the sea urchin Strongylocentrotus purpuratus. Science 314(5801): 941-52.
Stitzel, M. L. and Seydoux, G. (2007). Regulation of the oocyte-to-zygote transition. Science 316(5823): 407-8.
Townley, I.K., Roux, M.M. and Foltz, K.R. (2006). Signal transduction at fertilization: the Ca2+ release pathway in echinoderms and other invertebrate deuterostomes. Semin. Cell Dev. Biol. 17(2): 293-302.
Trimmer, J.S., Trowbridge, I.S. and Vacquier, V.D. (1985). Monoclonal antibody to a membrane glycoprotein inhibits the acrosome reaction and associated Ca2+ and H+ fluxes of sea urchin sperm. Cell. 40: 697–703.
Uehara, R., Hosoya, H. and Mabuchi, I. (2008). In vivo phosphorylation of regulatory light chain of myosin II in sea urchin eggs and its role in controlling myosin localization and function during cytokinesis. Cell Motil. Cytosk. 65(2): 100-15.
Vacquier, V.D., Swanson, W.J. and Hellberg, M.E. (1995). What have we learned about sea urchin sperm bindin? Dev. Growth Different. 37: 1–10.
Vacquier, V.D. and Moy, G.W. (1997). The fucose sulfate polymer of egg jelly binds to sperm REJ and is the inducer of the sea urchin sperm acrosome reaction. Dev. Biol. 192(1): 125-135.
Vilela-Silva, A.C., M.O. Castro, A.P. Valente, C.H. Biermann, and P.A. Mourao. (2002). Sulfated fucans from the egg jellies of the closely related sea urchins Strongylocentrotus droebachiensis and Strongylocentrotus pallidus ensure species-specific fertilization. J. Biol. Chem. 277:379-87.
Wong, J.L., Koppel, D.E., Cowan, A.E. and Wessel, G.M. (2007). Membrane hemifusion is a stable intermediate of exocytosis. Dev. Cell. 12(4): 653-9.
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